Biochemistry Videos & Books

Correct Answer -D

Correct Answer
Option A

Correct Answer d

Ans is c
t rna

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Correct Answer -D
D i.e. Involve phosphodiester bond formation with elongation
occurring in the 5'- 3' direction.
In both DNA and RNA synthesis, the general steps of initiation
elongation and termination occur in 5- 3' direction with the formation
of phosphodiester bondsQ.

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Correct Answer - D
There is no stored fuel in the brain, but it utilized 60% of total energy
under resting conditions.
Glucose is virtually the sole fuel for the brain, except in prolonged
starving when ketone bodies are the major source.
Fatty acids do not serve as fuel for the brain, because they are
bound to albumin in plasma; hence cannot cross the blood-brain
barrier.

Humans catabolize purines to uric acid. . But, first purines are catabolized to xanthine, which is further catabolized to purine.

Correct Answer - C Production of malonyl-CoA is the initial and rate-limiting step in the fatty acid synthesis. Acetyl-CoA needs to be converted to the activated form, which will serve as the donor of carbon units to the growing fatty acid chain. Malonyl-CoA, a 3-carbon compound is such an activated form. It is produced by carboxylation of acetyl-CoA, a reaction catalyzed by acetyl-CoA carboxylase. Acetyl-CoA carboxylase requires biotin as a cofactor. The reaction also requires HCO3 and ATP The reaction takes place in two steps: () Carboxylation of biotin involving HCO3 and ATP. (i) transfer of the carboxyl group to acetyl-CoA to form malonyl-CoA.

Correct Answer- D functionally, belong to the superfamily of amidohydrolases and phosphotriesterases Hydrolases --> All digestive enzymes (Pepsin,trypsin', Lipases, esterases), lysosomal enzymes'urease'and phosphatase.

Correct Answer-B Ans.is. B. Pyridoxine Pyridoxal phosphate is a coenzyme for many enzymes involved in amino 1309 acid metabolism, especially transamination and decarboxylation. It is also the cofactor of glycogen phosphorylase, where the phosphate group is catalytically important. In addition, it is important in steroid hormone action. Pyridoxal phosphate removes the hormone-receptor complex from DNA binding, terminating the action of the hormones.

Correct Answer -A Ans: A.Factor 2 • Vitamin K is a cofactor for the enzymatic conversion of glutamic acid (Glu) residues to gamma-carboxyglutamic acid (GLA) in vitamin K- dependent proteins, via the endoplasmic reticulum resident vitamin K-dependent gamma-glutamyl carboxylase. This carboxylase activity is found in essentially all mammalian tissues, and its reaction product, Gla, has been observed in both vertebrates and invertebrates; both play an important biological role in protein function. • Vitamin K--dependent clotting factor deficiency (VKCFD) is a rare autosomal recessive bleeding disorder that often presents with severe hemorrhage during infancy. • A rare inherited form of defective y-carboxylation resulting in the early onset of bleeding was first described by McMillan and Roberts in 1966 and subsequently has been termed vitamin K-dependent clotting factor deficiency (VKCFD). • Combined deficiency of vitamin K- dependent clotting factors II, VIJ IX, and X (and proteins C, S, and Z) is usually an acquired clinical problem, often resulting from liver disease, malabsorption, or warfarin overdose

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[9.2] A 59-year-old man is admitted to the intensive care unit for a myocar- dial infarction. He is given a ẞ-adrenergic antagonist and instructed to avoid emotional turmoil to decrease sympathetic stimulation of the heart. From a cellular perspective, sympathetic stimulation of the heart does which of the following?

Correct Answer: (B) Formation of methemoglobin

For those who picked Option A, here’s the catch!
Oxidized glutathione is actually the "used-up" version. Once it neutralizes oxidative stress, it turns into this oxidized form. What really matters is having reduced glutathione (the active form) to keep protecting RBCs.

*The main issue in G6PD deficiency is that RBCs can’t make enough reduced glutathione because of low NADPH. This leaves the cells vulnerable to oxidative stress, which leads to methemoglobin formation and, eventually, hemolysis.*

So, if you chose A, remember it’s the lack of *reduced glutathione* that causes trouble.

It’s a PYQ from JIPMER PG
smart question indeed! We got most of you on that one 👀.

A previously healthy, 27-year-old agricultural worker develops nausea, vomiting, abdominal cramps, cough with wheezing and dyspnoea, salivation, and lacrimation 1 hour after leaving work in a field. On examination, he is afebrile with a heart rate of 50/min and blood pressure of 90/55 mm Hg. Laboratory studies show plasma cholinesterase activity less than 50% of normal. Atropine is given intravenously, and his condition improves. He was most likely exposed to which of the following substances?

A Aflatoxin
B Cyclodiene
C Dioxin
D Ergot alkaloid
E Organophosphate

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Hey newbeezz!!!
I know there's so much to learn but isn't fun...
Okay so I guess in the childhood we all have heard the song, Baby.. Yeah that same which you tried to sing but for someone... .Ok let's not go that way...
So yeah the singer justin bieber is suffering from a condition ----------- which affects------- nerve....

A) bell's palsy, VIIth nerve
B) Bell's palsy, VIIIth nerve
C) Ramsay hunt syndrome, VIIIth nerve
D) Ramsay hunt syndrome, VIIth nerve
E) Sir, mujhe koi mili hi nhi...