The hallmark of MDS is the presence of tri-lineage dysplasia in the marrow.
Medical MCQ and notes
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Medical MCQ and notes (English)
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Medical MCQ and notes
14 Nov, 04:04
primary dietary source for folic acid is fresh uncooked fruits 🍇 and vegetables 🥒
Medical MCQ and notes
14 Nov, 04:03
macrocytic not megaloblastic anemia include liver disease, reticulocytosis, and myelodysplastic syndrome
Hypothyroidism ،
Alcoholism (COPD)
Hypothyroidism ،
Alcoholism (COPD)
Medical MCQ and notes
14 Nov, 04:02
Basophilic stippling= RBCs with fine to coarse bluish speckles as in Lead poisoning; Thalassemias; any severe stress on the bone marrow
Medical MCQ and notes
14 Nov, 04:01
Acanthocytosis: Hereditary abetalipoproteinemia, End-stage liver disease, Severe starvation, anorexia nervosa
Medical MCQ and notes
14 Nov, 04:01
Cold 🥶 Igm
Dx by direct anti globulin test ( coombs test )
Warm 🥵 IgG
The most important diagnostic test is the direct antiglobulin test (DAT), which is positive in >95% of cases. The antibody screen (indirect antiglobulin test) is positive in about 80% of cases.
Dx by direct anti globulin test ( coombs test )
Warm 🥵 IgG
The most important diagnostic test is the direct antiglobulin test (DAT), which is positive in >95% of cases. The antibody screen (indirect antiglobulin test) is positive in about 80% of cases.
Medical MCQ and notes
14 Nov, 04:00
Corticosteroids and splenectomy (the mainstays of therapy for warm immune hemolytic anemia)
Cold agglutinin disease should avoid cold temperatures and take precautions to keep the extremities warm. In patients who require further therapy, cyclophosphamide or chlorambucil given orally
Cold agglutinin disease should avoid cold temperatures and take precautions to keep the extremities warm. In patients who require further therapy, cyclophosphamide or chlorambucil given orally
Medical MCQ and notes
14 Nov, 04:00
The solubility test is usually positive if hemoglobin S comprises more than 10 to 20% of the hemoglobin. ▶️sickle cells anemia
Spherocytosis ▶️ The classic laboratory test for HS is the osmotic fragility test. • It is important to remember that increased osmotic fragility is not specific for HS; any cause of spherocytosis results in increased osmotic fragility.
Paroxysmal Nocturnal Hemoglobinuria 👹
The traditional diagnostic tests are the acidified serum (Ham’s) test and the sucrose hemolysis test. The sucrose hemolysis test is more sensitive, but the Ham’s test is more specific.
Demonstration of a decreased expression of GPI-anchored proteins on RBCs or leukocytes by flow cytometry with CD55 and CD 59 has been shown to be more sensitive than either of these tests
Spherocytosis ▶️ The classic laboratory test for HS is the osmotic fragility test. • It is important to remember that increased osmotic fragility is not specific for HS; any cause of spherocytosis results in increased osmotic fragility.
Paroxysmal Nocturnal Hemoglobinuria 👹
The traditional diagnostic tests are the acidified serum (Ham’s) test and the sucrose hemolysis test. The sucrose hemolysis test is more sensitive, but the Ham’s test is more specific.
Demonstration of a decreased expression of GPI-anchored proteins on RBCs or leukocytes by flow cytometry with CD55 and CD 59 has been shown to be more sensitive than either of these tests
Medical MCQ and notes
14 Nov, 03:59
Hereditary spherocytosis (HS) is the most common inherited hemolytic anemia in people in people of no
Northern European descent inherited in an autosomal dominant fashion
Northern European descent inherited in an autosomal dominant fashion
Medical MCQ and notes
13 Nov, 18:37
Sickle cells anemia
‼️Acute vaso-occlusive (painful) crise is most common cause of hospitalization
‼️Infections are the most common cause of death in sickle cell disease.🦠
‼️The acute chest syndrome is the second most common cause of hospitalization (after vasoocclusive crises)
‼️Acute vaso-occlusive (painful) crise is most common cause of hospitalization
‼️Infections are the most common cause of death in sickle cell disease.🦠
‼️The acute chest syndrome is the second most common cause of hospitalization (after vasoocclusive crises)
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