Neurology Updates @neurology_updates Channel on Telegram

Neurology Updates

@neurology_updates

All the atest articles, research and news from worlds leading Neurology Journals.

Discussion group
https://t.me/Professional_Medical_Discussion

Neurology Updates (English)

Are you passionate about staying up-to-date with the latest developments in the field of neurology? Look no further than the 'Neurology Updates' Telegram channel! This channel is dedicated to providing its subscribers with the most recent articles, research, and news from the world's leading neurology journals. Whether you are a neurologist, medical professional, student, or simply interested in learning more about the fascinating world of neurology, this channel is the perfect platform for you.

Stay informed about groundbreaking discoveries, innovative treatments, and important studies that are shaping the future of neurology. Engage in discussions with like-minded individuals who share your passion for the brain and nervous system. Connect with professionals from around the world and expand your knowledge in this ever-evolving field.

Join the 'Neurology Updates' Telegram channel today and become part of a vibrant community dedicated to advancing the field of neurology. Don't miss out on this valuable resource for staying informed and connected in the world of neurology!

Join our discussion group at: https://t.me/Professional_Medical_Discussion

Neurology Updates

22 Nov, 23:14

Exercise Linked to Lower Mortality Risk in Dementia Patients
https://www.medscape.com/viewarticle/exercise-linked-lower-mortality-risk-patients-dementia-2024a1000kza?src=rss

Physical activity, even at low intensity, was associated with a significantly lower risk for mortality in patients with dementia.
Medscape Medical News
251
Neurology Updates

22 Nov, 11:38

Interaction of methyl-CpG-binding protein 2 (MeCP2) with distinct enhancers in the mouse cortex

https://www.nature.com/articles/s41593-024-01808-y
446
Neurology Updates

22 Nov, 11:37

Predicting modular functions and neural coding of behavior from a synaptic wiring diagram

https://www.nature.com/articles/s41593-024-01784-3
359
Neurology Updates

22 Nov, 11:36

The BRAIN initiative: a pioneering program on the precipice

https://www.nature.com/articles/s41593-024-01811-3
338
Neurology Updates

21 Nov, 11:48

The cell-type underpinnings of the human functional cortical connectome

https://www.nature.com/articles/s41593-024-01812-2
548
Neurology Updates

21 Nov, 11:47

Tau filaments are tethered within brain extracellular vesicles in Alzheimer’s disease

https://www.nature.com/articles/s41593-024-01801-5
513
Neurology Updates

21 Nov, 11:46

Converging cortical axes

https://www.nature.com/articles/s41593-024-01722-3
496
Neurology Updates

21 Nov, 00:34

[In Context] Creative neurorehabilitation: the art of intervention

https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(24)00480-0/fulltext?rss=yes
583
Neurology Updates

19 Nov, 11:29

A top-down slow breathing circuit that alleviates negative affect in mice

https://www.nature.com/articles/s41593-024-01799-w
807
Neurology Updates

18 Nov, 17:51

AI Devices in Neurologyβ€”Moving From Diagnosis to Prognosis

https://jamanetwork.com/journals/jamaneurology/fullarticle/2826604
892
Neurology Updates

18 Nov, 17:50

Presentation, Findings, and Outcomes of IgG4-Related Pachymeningitis

https://jamanetwork.com/journals/jamaneurology/fullarticle/2826605
884
Neurology Updates

18 Nov, 17:49

Amyloid-Related Imaging Abnormalities in Clinical Trials of Gantenerumab in Early Alzheimer Disease

https://jamanetwork.com/journals/jamaneurology/fullarticle/2826606
623
Neurology Updates

18 Nov, 17:48

Trends in Gender, Racial, and Ethnic Representation Among US Neurology Faculty

https://jamanetwork.com/journals/jamaneurology/fullarticle/2826607
596
Neurology Updates

18 Nov, 12:41

A revised view of the role of CaMKII in learning and memory

https://www.nature.com/articles/s41593-024-01809-x
705
Neurology Updates

18 Nov, 07:43

SCD: Can Atrial Arrhythmias Predict Strokes?
https://www.medscape.com/viewarticle/scd-can-atrial-arrhythmias-predict-strokes-2024a1000kom?src=rss

Early detection of atrial arrhythmias may prevent strokes in sickle cell disease.
Medscape Medical News
748
Neurology Updates

18 Nov, 07:43

Less Fatigue in Multiple Sclerosis With CBT and Modafinil
https://www.medscape.com/viewarticle/less-fatigue-multiple-sclerosis-cbt-and-modafinil-2024a1000koh?src=rss

Modafinil and cognitive behavioral therapy, either alone or in combination, were associated with significantly less fatigue in patients with multiple sclerosis.
Medscape Medical News
784
Neurology Updates

17 Nov, 11:17

πŸ”΅ BPROAD Trial: Intensive BP Control in Type 2 Diabetes 🩺

πŸ”Ή Background
Optimal BP targets in Type 2 diabetes remain uncertain.

πŸ”Ή Methods
β€’ Enrolled 12,821 patients (age β‰₯50) across 145 sites in China
β€’ Randomised to BP targets: <120 mmHg (intensive) vs <140 mmHg (standard)
β€’ Follow-up: median 4.2 years

πŸ”Ή Results
β€’ Primary outcomes: 1.65 events/100 person-years (intensive) vs 2.09 events (standard)
β€’ HR: 0.79 (P<0.001)

⚠️ Higher hypotension & hyperkalemia in intensive group.

Conclusions: Intensive BP control (<120 mmHg) significantly reduces major CV events in T2DM.

For full article: https://www.nejm.org/doi/full/10.1056/NEJMoa2412006

#medicalresearch

@Updates_in_Medicine
746
Neurology Updates

15 Nov, 11:23

Emergence of a brainstem somatosensory tonotopic map for substrate vibration

https://www.nature.com/articles/s41593-024-01821-1
1,148
Neurology Updates

15 Nov, 11:22

Multimodal evaluation of network activity and optogenetic interventions in human hippocampal slices

https://www.nature.com/articles/s41593-024-01782-5
1,137
Neurology Updates

14 Nov, 11:53

🩺 AHA Guidelines on Managing Elevated BP in Acute Care

πŸ”— Full Guidelines 

πŸ”Ή No Routine Treatment
The AHA advises against routine antihypertensive treatment for asymptomatic elevated BP in acute settings.

πŸ”Ή Prioritise Hypertensive Emergencies
Immediate intervention is recommended only for cases with signs of target organ damage.

πŸ”Ή Accurate Measurement Matters
Ensure proper BP measurement technique and device calibration to prevent misreadings.

πŸ”Ή Plan for Outpatient Follow-Up
Restart home BP medications as appropriate and arrange outpatient follow-up for sustained care.

#medicalguidelines #guidelines

@Updates_in_Medicine
948
Neurology Updates

13 Nov, 11:20

Groundbreaking Diagnostic Tool for CNS Infections! πŸ”¬πŸ§ 

β–ͺ️Study Overview
πŸ”Ή UCSF’s CSF mNGS (Metagenomic Next-Generation Sequencing) test outperforms conventional methods, enabling broader pathogen detection in CNS infections.

β–ͺ️Key Findings
 β€’ 14.4% detection rate over 7 years from 4,828 samples.
 β€’ Higher Sensitivity: 63.1%, surpassing standard tests.
 β€’ Organisms Detected: 45.5% DNA viruses, 26.4% RNA viruses, 16.6% bacteria, 8.5% fungi, 2.9% parasites.

β–ͺ️Conclusions
Routine mNGS use is now justified for CNS infections, supporting faster, more accurate diagnosis.

For more: https://www.nature.com/articles/s41591-024-03275-1

#medicalresearch

@Updates_in_Medicine
573
Neurology Updates

13 Nov, 08:38

[Comment] Integrative medicine for the treatment of stroke
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02257-8/fulltext?rss=yes

Intracerebral haemorrhage is a devastating and less treatable type of stroke.1 Globally, intracerebral haemorrhage constitutes approximately one-third of all incident strokes and nearly half of the disability-adjusted life-years attributed to stroke.2 Burden of intracerebral haemorrhage is more prominent in low-income to middle-income countries, where unidentified and uncontrolled hypertension is an outstanding risk factor. Intracerebral haemorrhage accounts for 24% of incident stroke cases in China, and in some regions of central China it accounts for 60% of all strokes.
609
Neurology Updates

13 Nov, 08:38

[Articles] Traditional Chinese medicine FYTF-919 (Zhongfeng Xingnao oral prescription) for the treatment of acute intracerebral haemorrhage: a multicentre, randomised, placebo-controlled, double-blind, clinical trial
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02261-X/fulltext?rss=yes

This large, randomised, placebo-controlled, double-blind, clinical trial showed no effect of the traditional Chinese medicine herbal compound FYTF-919 on functional recovery, survival, and health-related quality of life in patients with moderate to severe intracerebral haemorrhage. The results reaffirm the need for methodologically rigorous, randomised controlled trials to evaluate the effectiveness of existing therapies, including traditional Chinese medicines that are already in widespread use throughout the world.
616
Neurology Updates

12 Nov, 14:27

Seven-year performance of a clinical metagenomic next-generation sequencing test for diagnosis of central nervous system infections
https://www.nature.com/articles/s41591-024-03275-1

Nature Medicine, Published online: 12 November 2024; doi:10.1038/s41591-024-03275-1 (https://www.nature.com/articles/s41591-024-03275-1)Next-generation metagenomic testing increases the accuracy and sensitivity of the etiology of central nervous system infections in hospitalized patients.
688
Neurology Updates

11 Nov, 18:48

Epileptiform Electrographic Patterns After Cardiac Arrest

https://jamanetwork.com/journals/jamaneurology/fullarticle/2826164
834
Neurology Updates

11 Nov, 18:47

Family Trajectories Preceding Dementia in the US and UK

https://jamanetwork.com/journals/jamaneurology/fullarticle/2826165
762
Neurology Updates

11 Nov, 18:46

Gantenerumab in Dominantly Inherited Alzheimer Diseaseβ€”Reply

https://jamanetwork.com/journals/jamaneurology/fullarticle/2826166
641
Neurology Updates

11 Nov, 18:45

Gantenerumab in Dominantly Inherited Alzheimer Disease

https://jamanetwork.com/journals/jamaneurology/fullarticle/2826167
634
Neurology Updates

11 Nov, 16:48

TYK2 regulates tau levels, phosphorylation and aggregation in a tauopathy mouse model

https://www.nature.com/articles/s41593-024-01777-2
687
Neurology Updates

11 Nov, 16:47

Astrocyte transcriptomic changes along the spatiotemporal progression of Alzheimer’s disease

https://www.nature.com/articles/s41593-024-01791-4
744
Neurology Updates

10 Nov, 12:07

Full Guidelines above


@Updates_in_Medicine
895
Neurology Updates

08 Nov, 11:57

DIRECT-MT Trial Findings on Stroke Treatment 🧠

πŸ”Ή IV Thrombolysis for Stroke
Guidelines recommend IV thrombolysis within 4.5 hours for eligible stroke patients who are also candidates for mechanical thrombectomy.

πŸ”Ή Enhanced Outcomes
Improves functional outcomes and may lower mortality when given early.

πŸ”Ή Shared Decision-Making
Discuss risks and benefits of IV thrombolysis with patients or surrogates before thrombectomy.

πŸ”Ή Conclusions
IV thrombolysis remains critical in optimising emergency stroke care


FULL GUIDELINES


#medicalguidelines #guidelines #medicalresearch
1,361
Neurology Updates

07 Nov, 10:30

πŸ”΄ Drug Combo Tied to Functional Improvement After Stroke
https://www.medscape.com/viewarticle/drug-combo-tied-functional-improvement-after-stroke-2024a1000jvs?src=rss

The largest and the latest controlled multicenter trial to test edaravone plus dexborneol for acute stroke has confirmed improved recovery with no safety issues relative to placebo.
Medscape Medical News
1,225
Neurology Updates

07 Nov, 10:28

[Articles] Deep learning model for automated diagnosis of moyamoya disease based on magnetic resonance angiography
https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(24)00467-X/fulltext?rss=yes

This study highlights the efficacy of CNN model in the automated diagnosis of MMD on MRA images, easing the workload on radiologists and promising integration into clinical workflows.
1,162
Neurology Updates

06 Nov, 14:39

Deep RNA sequencing of human dorsal root ganglion neurons reveals somatosensory mechanisms

https://www.nature.com/articles/s41593-024-01795-0
1,247
Neurology Updates

05 Nov, 13:42

Spatially resolved gene signatures of white matter lesion progression in multiple sclerosis

https://www.nature.com/articles/s41593-024-01765-6
1,200
Neurology Updates

05 Nov, 13:41

Cell type mapping reveals tissue niches and interactions in subcortical multiple sclerosis lesions

https://www.nature.com/articles/s41593-024-01796-z
984
Neurology Updates

05 Nov, 13:40

Mapping out multiple sclerosis with spatial transcriptomics

https://www.nature.com/articles/s41593-024-01798-x
552
Neurology Updates

05 Nov, 06:10

Pro-urokinase a Less Expensive Thrombolytic for Stroke
https://www.medscape.com/viewarticle/pro-urokinase-less-expensive-thrombolytic-stroke-2024a1000juf?src=rss

Recombinant human pro-urokinase was non-inferior to alteplase in achieving an excellent functional outcome in patients with acute ischemic stroke but had a lower ICH rate.
Medscape Medical News
626
Neurology Updates

04 Nov, 18:32

Remembering the Physician’s Humanityβ€”Physicians Are Humans Too

https://jamanetwork.com/journals/jamaneurology/fullarticle/2825845
690
Neurology Updates

04 Nov, 18:31

Deferiprone in Alzheimer Disease

https://jamanetwork.com/journals/jamaneurology/fullarticle/2825846
623
Neurology Updates

04 Nov, 18:30

Immediate or Delayed Statin in Acute Atherosclerotic Ischemiaβ€”Reply

https://jamanetwork.com/journals/jamaneurology/fullarticle/2825847
587
Neurology Updates

04 Nov, 18:29

Immediate or Delayed Statin in Acute Atherosclerotic Ischemia

https://jamanetwork.com/journals/jamaneurology/fullarticle/2825848
532
Neurology Updates

04 Nov, 16:43

The role of motor cortex in motor sequence execution depends on demands for flexibility

https://www.nature.com/articles/s41593-024-01792-3
608
Neurology Updates

04 Nov, 16:42

Leveraging deep single-soma RNA sequencing to explore the neural basis of human somatosensation

https://www.nature.com/articles/s41593-024-01794-1
580
Neurology Updates

04 Nov, 10:37

πŸ”΄ New Data to Alter Planned ICH Guidelines
https://www.medscape.com/viewarticle/new-data-alter-planned-intracerebral-hemorrhage-guidelines-2024a1000jt8?src=rss

European hemorrhagic stroke guidelines planned for release in early 2024 are on hold to accommodate newly published data, some of which will alter recommendations.
Medscape Medical News
680
Neurology Updates

04 Nov, 01:37

Plasma biomarkers in chronic single moderate/severe traumatic brain injury

https://academic.oup.com/brain/article/147/11/3641/7866920?rss=1
844
Neurology Updates

04 Nov, 01:36

Delineating three distinct spatiotemporal patterns of brain atrophy in Parkinson’s disease

https://academic.oup.com/brain/article/147/11/3702/7832343?rss=1
642
Neurology Updates

04 Nov, 01:35

Motor compensation in Parkinson’s disease: an empirical challenge with clinical implications

https://academic.oup.com/brain/article/147/11/3648/7824337?rss=1
624
Neurology Updates

04 Nov, 01:34

Our evolving understanding of the impact of primary HIV infection on brain health

https://academic.oup.com/brain/article/147/11/3643/7819210?rss=1
649
Neurology Updates

03 Nov, 11:23

πŸ“Š Understanding Body Roundness Index (BRI)

The Body Roundness Index (BRI) is a geometrical measure of body fat distribution based on height and waist circumference 🧬.

Unlike BMI, which considers only height and weight, BRI captures body fat distribution, adding valuable insights into health risk.

Latest Research Findings on BRI:

1. JAMA Network Open, 2024: This study uncovered a U-shaped association between BRI and all-cause mortalityβ€”showing both low and high BRI levels linked with higher mortality risks.
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2819558

2. Nature Scientific Reports, 2024: Another study revealed a strong link between food insecurity and elevated BRI and ABSI (body shape index), particularly affecting women across different age groups. The findings underscore food insecurity as a critical factor in obesity and body fat distribution.
https://www.nature.com/articles/s41598-024-74108-x

#medicalresearch

@Updates_in_Medicine
624
Neurology Updates

31 Oct, 15:28

Integration across biophysical scales identifies molecular and cellular correlates of person-to-person variability in human brain connectivity

https://www.nature.com/articles/s41593-024-01788-z
254
Neurology Updates

31 Oct, 07:24

New Data for DOACs in Cerebral Venous Thrombosis
https://www.medscape.com/viewarticle/new-evidence-supports-doacs-cerebral-venous-thrombosis-2024a1000jqk?src=rss

New evidence supports the use of direct oral anticoagulants in the treatment of cerebral venous thrombosis.
Medscape Medical News
365
Neurology Updates

28 Oct, 20:53

Ernest Arenas (1962–2024)

https://www.nature.com/articles/s41593-024-01797-y
796
Neurology Updates

28 Oct, 20:22

Neonatal Neurocritical Care Training

https://jamanetwork.com/journals/jamaneurology/fullarticle/2824952
716
Neurology Updates

28 Oct, 20:21

A Clown With Traumatic Brain Injury

https://jamanetwork.com/journals/jamaneurology/fullarticle/2824953
569
Neurology Updates

28 Oct, 20:21

Mobile Stroke Unit Management After Acute Ischemic Stroke

https://jamanetwork.com/journals/jamaneurology/fullarticle/2824954
584
Neurology Updates

28 Oct, 20:19

Mobile Stroke Unitsβ€”Time for Legislation and Renumeration

https://jamanetwork.com/journals/jamaneurology/fullarticle/2824955
566
Neurology Updates

28 Oct, 12:21

πŸ”΄ Dapagliflozin Safe and Effective in CKD Stages 4 and 5
https://www.medscape.com/viewarticle/dapagliflozin-safe-and-effective-ckd-stages-4-and-5-2024a1000jm4?src=rss

In a first renal outcome trial of its kind, the SGLT2 inhibitor showed favorable outcomes in the most advanced stages of CKD.
718
Neurology Updates

27 Oct, 10:56

πŸ”΄ Follow Updates in Medicine on X (formerly Twitter) & Threads (meta) for the latest, trending medical research, news, and guidelines.

πŸ”— X (Twitter) - https://x.com/medic_updates

πŸ”— Treads - https://www.threads.net/@updates_in_medicine?igshid=MzRlODBiNWFlZA==

Stay informed, stay updated!
527
Neurology Updates

25 Oct, 13:57

Cardiac Monitoring Is Crucial in Neuromuscular Disorder Care
https://www.medscape.com/viewarticle/cardiac-monitoring-crucial-neuromuscular-disorder-care-2024a1000j5i?src=rss

Heart dysfunction is common, and maternal carriers may be affected too.
1,153
Neurology Updates

25 Oct, 10:41

A trainee-informed model for undergraduate neuroscience research programs serving marginalized students

https://www.nature.com/articles/s41593-024-01790-5
1,100
Neurology Updates

25 Oct, 06:39

🧠 2024 Stroke Prevention Guidelines from AHA / ASA

Full Guidelines here - https://t.me/Updates_in_Medicine/2269

Key updates from AHA/ASA :

 1. πŸ’Š Aspirin Use: Recommended only for high-risk cardiovascular patients. Routine use is discouraged due to bleeding risks.

 2. πŸ₯— Lifestyle Changes: Focus on Mediterranean or DASH diets, regular physical activity, and smoking cessation.

 3. πŸ’‰ Blood Pressure Management: Aim for a target of <130/80 mm Hg to lower stroke risk.

 4. 🩸 Diabetes Control: Maintain HbA1c <7% for those with Type 2 diabetes to prevent stroke.

 5. βš•οΈ Lipid Management: Statins are recommended for patients at high risk of cardiovascular events.



@Updates_in_Medicine
783
Neurology Updates

24 Oct, 11:34

Cognitive Decline and Antihypertensive Use: New Data
https://www.medscape.com/viewarticle/cognitive-decline-and-antihypertensive-use-new-data-2024a1000isw?src=rss

Deprescribing antihypertensive medications is associated with reduced cognitive decline among older residents of nursing homes, particularly those with dementia.
953
Neurology Updates

24 Oct, 08:45

🧠 New Insulin-Based Tech for Drug Delivery in Alzheimer’s
https://www.pnas.org/doi/abs/10.1073/pnas.2407936121

β€’ Researchers developed insulin-fusion proteins that target hippocampal neurons, commonly damaged in Alzheimer’s disease.

β€’ This method bypasses the blood-brain barrier (BBB), allowing efficient delivery of protein drugs directly to affected areas in the brain.

β€’ This innovation could significantly improve drug therapies for neurodegenerative diseases.


@Updates_in_Medicine
946
Neurology Updates

23 Oct, 12:31

Early Biomarkers in the Detection of Traumatic Brain Injury
https://www.medscape.com/viewarticle/early-biomarkers-detection-traumatic-brain-injury-2024a1000is2?src=rss

Levels of the biomarkers GFAP, UCH-L1, and MAP-2 spiked within 30 minutes of traumatic brain injury, with GFAP diagnosing intracranial lesions and predicting critical outcomes most accurately.
1,167
Neurology Updates

22 Oct, 18:11

Heart Attack, Stroke Survivors at High Risk for Long COVID
https://www.medscape.com/viewarticle/heart-attack-stroke-survivors-high-risk-long-covid-2024a1000ipe?src=rss

New data: Researchers cautioned those with previous CVD have a higher risk of developing long COVID and should take steps to avoid infection.
1,278
Neurology Updates

22 Oct, 11:13

Unique Naturalistic Brain Mapping Study Offers Rare Insight
https://www.medscape.com/viewarticle/unique-naturalistic-brain-mapping-study-offers-rare-insight-2024a1000ipz?src=rss

A unique single-participant precision brain mapping study offered rare insight into how sleep, mood, physical activity, and heart rate affect brain connectivity weeks later.
1,322
Neurology Updates

22 Oct, 01:08

[Personal View] Uncovering the genetic basis of Parkinson's disease globally: from discoveries to the clinic

https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(24)00378-8/fulltext?rss=yes
1,307
Neurology Updates

22 Oct, 01:07

[Comment] The global dimension of Parkinson's disease genetics

https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(24)00435-6/fulltext?rss=yes
1,167
Neurology Updates

21 Oct, 16:49

Digital Biomarkers for Neurodegenerative Disease

https://jamanetwork.com/journals/jamaneurology/fullarticle/2824568
1,163
Neurology Updates

21 Oct, 16:48

Hearing Loss, Incident Parkinson Disease, and Treatment With Hearing Aids

https://jamanetwork.com/journals/jamaneurology/fullarticle/2824569
708
Neurology Updates

21 Oct, 16:47

Risk of Inflammatory Central Nervous System Diseases After Tumor Necrosis Factor–Inhibitor Treatment

https://jamanetwork.com/journals/jamaneurology/fullarticle/2824570
600
Neurology Updates

21 Oct, 16:46

Development and Validation of a Clinical Score to Predict Epilepsy After Cerebral Venous Thrombosis

https://jamanetwork.com/journals/jamaneurology/fullarticle/2824571
597
Neurology Updates

21 Oct, 16:45

Genome Sequencing After Exome Sequencing in Pediatric Epilepsy

https://jamanetwork.com/journals/jamaneurology/fullarticle/2824572
684
Neurology Updates

21 Oct, 12:54

Opicapone in Early PD: Time to Revisit Off-Label COMT Use?
https://www.medscape.com/viewarticle/opicapone-early-parkinsons-time-revisit-label-comt-use-2024a1000im9?src=rss

New phase 3 results should reopen discussion about the off-label use of COMT inhibitors in early Parkinson's disease, experts said.
723
Neurology Updates

20 Oct, 12:53

Early Promise for Vaccine in Parkinson's and MSA
https://www.medscape.com/viewarticle/early-promise-vaccine-parkinsons-and-multiple-system-atrophy-2024a1000im2?src=rss

An experimental immunotherapy candidate targets toxic species of alpha-synuclein and was well tolerated in an ongoing, two-dose phase 1b study.
933
Neurology Updates

19 Oct, 11:49

The 'Enormous' Promise of Focused Ultrasound Now Coming True
https://www.medscape.com/viewarticle/enormous-promise-focused-ultrasound-now-coming-true-2024a1000ilp?src=rss

After decades of research, the field of focused ultrasound is exploding with new advances β€” promising safer, more effective treatments for a wide range of conditions.
1,127
Neurology Updates

19 Oct, 06:42

[Articles] Treatment for essential tremor: a systematic review and Bayesian Model-based Network Meta-analysis of RCTs

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(24)00468-1/fulltext?rss=yes
1,093
Neurology Updates

18 Oct, 09:38

Positive Phase 3 Results for First-in-Class Parkinson's Med
https://www.medscape.com/viewarticle/positive-phase-3-results-first-class-parkinsons-med-2024a1000ijv?src=rss

An experimental first-in-class oral selective partial D1/D5 dopamine receptor agonist for Parkinson's significantly reduce disease burden in two phase 3 trials.
1,126
Neurology Updates

17 Oct, 11:28

air pollution exposure and risk for pd, dyskinesia: new data
https://www.medscape.com/viewarticle/air-pollution-exposure-and-risk-parkinsons-disease-and-2024a1000ige?src=rss

increased exposure to nitrogen dioxide and particulate matter in the air was associated with an increased risk for parkinson's disease and dyskinesia.
275
Neurology Updates

16 Oct, 17:40

Can Antiseizure Drugs Increase Cardiovascular Risk?
https://www.medscape.com/viewarticle/can-antiseizure-drugs-increase-cardiovascular-risk-2024a1000ik5?src=rss

Almost one third of an observed association between epilepsy and new-onset cardiovascular events is attributable to the use of antiseizure medications, data suggest.
Medscape Medical News
460
Neurology Updates

16 Oct, 11:53

πŸš€ Reach Over 200,000 Medical Subscribers!

Promote your content to a large, targeted audience on our Telegram channels.

Contact Admin for promotions:
@Updates_in_Medicine_Admin
540
Neurology Updates

16 Oct, 10:35

Rastermap: a discovery method for neural population recordings

https://www.nature.com/articles/s41593-024-01783-4
575
Neurology Updates

16 Oct, 10:34

Integrating brainstem and cortical functional architectures

https://www.nature.com/articles/s41593-024-01787-0
489
Neurology Updates

16 Oct, 10:12

Nephrologists Urge Active Search for Chronic Kidney Disease
https://www.medscape.com/viewarticle/nephrologists-urge-active-search-chronic-kidney-disease-2024a1000icc?src=rss

Early detection of the disease is crucial because available medications can delay or halt its progression.
445
Neurology Updates

15 Oct, 17:57

The hippocampal CA2 region discriminates social threat from social safety

https://www.nature.com/articles/s41593-024-01771-8
606
Neurology Updates

15 Oct, 17:56

A cross-disease resource of living human microglia identifies disease-enriched subsets and tool compounds recapitulating microglial states

https://www.nature.com/articles/s41593-024-01764-7
567
Neurology Updates

15 Oct, 09:32

Novel Treatment Alleviates Postherpetic Neuralgia
https://www.medscape.com/viewarticle/crisugabalin-alleviates-postherpetic-neuralgia-symptoms-2024a1000i8z?src=rss

Two different doses of crisugabalin resulted in significantly greater pain reductions in adults with postherpetic neuralgia than placebo in a phase 3 trial.
Medscape Medical News
600
Neurology Updates

14 Oct, 16:27

Skin Biopsies vs CSF in the Diagnosis of Prion Diseases

https://jamanetwork.com/journals/jamaneurology/fullarticle/2824416
703
Neurology Updates

14 Oct, 16:26

Collaborative Dementia Care During the New Therapeutic Era

https://jamanetwork.com/journals/jamaneurology/fullarticle/2824415
621
Neurology Updates

14 Oct, 16:25

Crossed Clonus Response

https://jamanetwork.com/journals/jamaneurology/fullarticle/2824417
520
Neurology Updates

14 Oct, 10:53

Integrated multimodal cell atlas of Alzheimer’s disease

https://www.nature.com/articles/s41593-024-01774-5
666
Neurology Updates

14 Oct, 09:33

sNFl and sGFAP Predict MS Disability in Unique Ways
https://www.medscape.com/s/viewarticle/snfl-and-sgfap-predict-ms-disability-unique-ways-2024a1000i8x?src=rss

Serum glial fibrillary acidic protein (sGFAP) is quickly maturing as a biomarker to predict disability in patients with multiple sclerosis (MS).
MDedge News
619
Neurology Updates

14 Oct, 02:21

[Correspondence] The European expertise network for open microvascular surgery

https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(24)00409-5/fulltext?rss=yes
707
Neurology Updates

13 Oct, 19:41

πŸ”¬ Autoantibodies Targeting Nephrin in Podocytopathies

πŸ“„ Key Points:

β€’ The study by Hengel et al. claims to show autoantibodies targeting nephrin in patients with podocytopathies like minimal change disease and focal segmental glomerulosclerosis (FSGS).
β€’ However, they did not directly detect antinephrin autoantibodies using Western blots or ELISAs.

πŸ’‘ Interesting Findings:

β€’ The study relies on indirect methods, using agarose protein G beads to recover recombinant nephrin, suggesting potential autoantibody presence.

πŸ”‘ Conclusion:
More direct evidence is needed to confirm the presence of antinephrin autoantibodies in podocytopathies.

πŸ“– Full article:
https://www.nejm.org/doi/full/10.1056/NEJMc2410840

@The_NEJM
717
Neurology Updates

13 Oct, 12:07

High Cadmium Level Associated With Cognitive Impairment Risk
https://www.medscape.com/viewarticle/high-cadmium-level-associated-cognitive-impairment-risk-2024a1000i2s?src=rss

Higher levels of the heavy metal cadmium were associated with an increased risk for global cognitive impairment among White, but not Black, adults.
837
Neurology Updates

12 Oct, 11:38

πŸ”΄πŸ”΄ We are back on Instagram

Join for latest trending medical research, news and guidelines

https://www.instagram.com/updates_in_medicine
1,071
Neurology Updates

12 Oct, 10:02

Full Cognitive Recovery After Brain RT Possible for Many
https://www.medscape.com/viewarticle/full-cognitive-recovery-after-brain-radiotherapy-possible-2024a1000i2k?src=rss

A sizeable proportion of patients with cancer who experience cognitive decline after radiation treatment for brain metastases may regain full neurocognitive function within 6 months.
Medscape Medical News
1,038

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