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PYQ
Short Notes

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PYQ
Answer 191th with explanations 👇👇

Generalized granuloma annulare; benign dermatosis. Trunk is usually involved, also neck, extremities, face, scalp, palms & soles. Lesions: widespread papules to annular plaques to large, discolored patches from yellow to violaceous.


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QUES. 191

A 64-year-old man presented with a two-year history of this asymptomatic skin condition, which was symmetrically distributed over his trunk, arms and legs. Laboratory tests demonstrated a raised fasting blood glucose level. What is the likely diagnosis?


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Approach to diarrhea


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Approach to suspected peripheral artery disease

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Answer 187th with explanations 👇👇
Chilaiditi's sign; describes the incidental radiographic finding of the bowel positioned between the right diaphragm and the liver. This is often misdiagnosed as pneumoperitoneum or free air under the diaphragm, which may lead to unnecessary investigations or surgical procedures

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Ques 187 .
A middle aged male presented for pre operative evaluation. What is the noticeable radiologic sign & diagnosis?


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Ques 184 .
A middle aged woman presented for redness in her eyes. She also endorsed diffuse joint pain & pain with urination. What is the most likely diagnosis?

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Answer 184th with explanations 👇👇

Reactive arthritis: postinfectious autoimmune condition preceded by bacterial infection of the GI or urinary tract. It is categorized as a seronegative spondyloarthropathy & associated w/ HLA-B27. The classic triad (arthritis, conjunctivitis, urethritis) is seen


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183rd question explanation

The poly-A tail is a long chain of adenine nucleotides that is added to a messenger RNA (mRNA) molecule
during RNA processing to increase the stability of the molecule. Additionally, the poly-A tail allows the mature
messenger RNA molecule to be exported from the nucleus and translated into a protein by ribosomes
in the cytoplasm

👉 Important point:
Translation of the poly (A) tail plays crucial roles in mRNA surveillance
translation repression and protein destabilization. Because poly-lysine synthesis via translation of the poly (A) mRNA tail leads to translation arrest and protein degradation by the proteasome
👉 Answer: Poly-lysine ✅

Ref: Harper's Ilustrated Biochemistry, 31st Edition page 390

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