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Enclomiphene is one of the isomers of clomiphene citrate, used to treat testosterone-related issues in men, as well as certain fertility problems. Clomiphene citrate consists of two isomers: enclomiphene and zuclomiphene. Enclomiphene is the more active isomer and offers clear advantages over standard clomiphene.
Key advantages of enclomiphene over regular clomiphene:
1. Specific action on testosterone: Enclomiphene more effectively increases testosterone levels in men without causing estrogen-related side effects. Zuclomiphene, the other isomer in clomiphene, may have partial estrogenic activity, making clomiphene citrate less selective in its action.
2. Fewer side effects: Since enclomiphene lacks estrogenic properties, it causes fewer side effects like increased estrogen, gynecomastia, fluid retention, and mood swings, which can occur with regular clomiphene.
3. Faster action: Enclomiphene works faster and provides more predictable results for boosting testosterone, which is important for patients aiming for specific treatment outcomes.
4. Longer-lasting estrogen control: In standard clomiphene, zuclomiphene remains in the body longer, potentially causing unwanted effects. Isolated enclomiphene offers better control over estrogen-related side effects.
Thus, enclomiphene is a refined version of clomiphene for men who need to boost testosterone or treat fertility issues, providing more targeted action with fewer side effects.
Typical dosage of enclomiphene:
Standard dose: 12.5–25 mg per day. A lower dose (12.5 mg) is often used to maintain normal testosterone levels, while 25 mg may be prescribed for a more active testosterone boost.
Treatment duration:
Course length: A course of enclomiphene can range from 4 to 12 weeks, depending on the treatment goal and individual response. For testosterone elevation, a 6–8 week course is common, followed by hormone level testing to determine further use.
Monitoring and tests:
During treatment, it's advisable to regularly monitor testosterone and estrogen levels to avoid unwanted side effects and adjust the dosage if needed.
Post-treatment:
Post-cycle therapy (PCT) may not be necessary, as enclomiphene does not suppress testosterone production like some other drugs. However, it is recommended to check hormone levels after the course for accuracy.
It’s crucial to consult a doctor or endocrinologist before starting enclomiphene to determine individual needs and ensure safe use.