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Key Findings
โข Distinct tumour microregions with unique genetics, size, and activity
โข 3D tumour mapping reveals immune hot/cold zones, metabolic centres, & antigen-rich edges
โข Increased metabolic activity at tumour centres; antigen presentation higher at edges
โข Variable T cell infiltration; macrophages predominantly at tumour boundaries
โข Provides insights into tumour evolution & microenvironment interactions
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