A 60 year old presents to the ER with severe chest pain. The pain began when he was climbing the stairs at his house and has persisted despite rest. He gives a previous history of similiar episodes of chest pain but they always resolved when he took rest. The pain is associated with breathlessness and sweating. He is a known case of type II diabetes mellitus and hypertension. He smokes 1 pack of cigarettes per day
On examination: temperature - 98.6°F, HR - 100/min, BP - 150/90mm Hg, SpO2 - 99% on room air, 12-lead ECG shows ST elevation in leads I,aVL, V5 and V6 and ST depression in leads II, III and aVF. The nursing staff informs you that patient transfer to the nearest hospital with a cardiac cath lab will take 45 minutes. Which of the following is the most appropriate next step?