NEET PG/NEXT/INICET/FMGE👨‍⚕🧑‍⚕👩‍⚕

Mrs. Rao, a 50 year old woman with a 10 day history of nasal discharge, headache that increases on bending down and pain over the medial canthus, now presents to the outpatient department with high grade fever, chills, headache and bilateral proptosis. On further inquiry, it is brought to light that the proptosis began in the right eye and since yesterday the left eye has also been affected. On examination, her pulse rate is 56 beats per minute, BP is 150/96mm of Hg, the temperature is 102°F. There is periorbital edema, proptosis and ophthalmoplegia. The pupillary response is sluggish. Fundoscopy reveals papilloedema. Which of the following is the most probable diagnosis?

Theme: Reperfusion strategy for myocardial infarction
A 60 year old presents to the ER with severe chest pain. The pain began when he was climbing the stairs at his house and has persisted despite rest. He gives a previous history of similiar episodes of chest pain but they always resolved when he took rest. The pain is associated with breathlessness and sweating. He is a known case of type II diabetes mellitus and hypertension. He smokes 1 pack of cigarettes per day
On examination: temperature - 98.6°F, HR - 100/min, BP - 150/90mm Hg, SpO2 - 99% on room air, 12-lead ECG shows ST elevation in leads I,aVL, V5 and V6 and ST depression in leads II, III and aVF. The nursing staff informs you that patient transfer to the nearest hospital with a cardiac cath lab will take 45 minutes. Which of the following is the most appropriate next step?