Immunology & Serology Review Questions Telegram Posts

Hey guys. Please take time to read this. Thanks to Susmita for the heads up 😊

Immunology & Serology Review Questions pinned «MUST KNOW 🔊 ADCC receptors: CD16 and CD32 Please add CD32 in the notes. It is added in the new edition of Steven’s. Good to note also that these receptors (CD32 and CD16) for ADCC are not only present in the NK Cells but ARE ALSO PRESENT in monocytes…»

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MUST KNOW 🔊

2 IgGs are required to successfully form the Activation Unit.

In the new edition of Steven’s, the ideal number of IgG bound to C1q to efficiently activate the complement is 6.

6 adjacent (30-40nm distance) IgGs.

IgG4 cannot activate complement because 1 IgG4 is far (>40nm distance) to another IgG4.

Last for tonight 😅

MUST KNOW 🔊

ADCC receptors: CD16 and CD32

Please add CD32 in the notes. It is added in the new edition of Steven’s.

Good to note also that these receptors (CD32 and CD16) for ADCC are not only present in the NK Cells but ARE ALSO PRESENT in monocytes, macrophages, and neutrophils.

THEREFORE, ADCC is not unique to NK Cell.

NICE TO KNOW ⚜️

NK cell can kill damaged cell, virally infected cell, or tumor cell as fast as 30-60 minutes

NICE TO KNOW ⚜️

It will take as fast as 20 Seconds for a neutrophil/macrophage to eat a heavily opsonized bacterial cell.

Most especially if the opsonin used is CRP. 😌

UPDATE ‼️


CRP half-life in the 5th edition of Steven’s is already 18 hours instead of 5-7 hours.


CRP half-life : 18 hours
Onset of Increase : 4-6 hours
Peak : 48 hours

Good day everyone! This is the final table for the Enzyme Labeled Immunoassay. Please write the necessary correction in your notes. Thank you very much!

You all did very well today 🤩🎉. Virtual hug ❤️ Keep on praying guys. We are praying and rooting for all of you. One last push ❤️ 🥳