- Spike (S) protein binds to ACE2 receptor.
- TMPRSS2 will cleave the S protein into S1 and S2 fragments , in order to activate the S protein.
S1 binds to ACE2 receptor and S2 binds to TMPRSS2 , inducing viral entry to the cell.
* TMPRSS2 : transmembrane protease serine-2 receptor
#ID_virology_Micro_TBL1