анозогнозия и коморбидные расстройства

Геологи смоделировали деформацию земной коры в ответ на истончение ледников

The Early Bronze Age Unetice culture has traditionally been thought of descending from Bell Beaker individuals, with perhaps limited input from the southeast (Carpathian Basin). However, the new genetic data supports yet another genetic turnover originating from regions northeast of Bohemia. Remarkably, also 80 percent of the early Unetice Y-lineages are new to Bohemia, some of which are previously found in individuals from north-eastern Europe, providing clues to where they originated from. "This finding was very surprising to us archaeologists as we did not expect to see such clear patterns, even though the region has played a critical role, e.g. in the emerging trade of amber from the Baltic and became an important trading hub during the Bronze and Iron Ages," adds co-author and co-PI Michal Ernée from the Czech Academy of Sciences.

Blood groups of Neandertals and Denisova decrypted

Abstract

Blood group systems were the first phenotypic markers used in anthropology to decipher the origin of populations, their migratory movements, and their admixture. The recent emergence of new technologies based on the decoding of nucleic acids from an individual’s entire genome has relegated them to their primary application, blood transfusion. Thus, despite the finer mapping of the modern human genome in relation to Neanderthal and Denisova populations, little is known about red cell blood groups in these archaic populations. Here we analyze the available high-quality sequences of three Neanderthals and one Denisovan individuals for 7 blood group systems that are used today in transfusion (ABO including H/Se, Rh (Rhesus), Kell, Duffy, Kidd, MNS, Diego). We show that Neanderthal and Denisova were polymorphic for ABO and shared blood group alleles recurrent in modern Sub-Saharan populations. Furthermore, we found ABO-related alleles currently preventing from viral gut infection and Neanderthal RHD and RHCE alleles nowadays associated with a high risk of hemolytic disease of the fetus and newborn. Such a common blood group pattern across time and space is coherent with a Neanderthal population of low genetic diversity exposed to low reproductive success and with their inevitable demise. Lastly, we connect a Neanderthal RHD allele to two present-day Aboriginal Australian and Papuan, suggesting that a segment of archaic genome was introgressed in this gene in non-Eurasian populations. While contributing to both the origin and late evolutionary history of Neanderthal and Denisova, our results further illustrate that blood group systems are a relevant piece of the puzzle helping to decipher it.

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Dinosaurs were in decline before the end, according to new study

> The death of the dinosaurs 66 million years ago was caused by the impact of a huge asteroid on the Earth. However, palaeontologists have continued to debate whether they were already in decline or not before the impact.

> In a new study, published today in the journal Nature Communications, an international team of scientists, which includes the University of Bristol, show that they were already in decline for as much as ten million years before the final death blow.

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From a MAYA collaboration numerical relativity simulation of an neutron star-black hole binary merger. Focused on the merging objects showing the disruption of the neutron star. Credit: Deborah Ferguson (UT Austin), Bhavesh Khamesra (Georgia Tech), Karan Jani (Vanderbilt)

src: Astrophysicists detect first black hole-neutron star mergers

Parasites manipulate praying mantis's polarized-light perception, causing it to jump into water

> Researchers have revealed that praying mantis (mantids) infected with parasitic hairworms are attracted to horizontally polarized light that is strongly reflected off the surface of water, which causes them to enter the water. In a world-first, these research results demonstrate that parasites can manipulate the host's specific light perception system to their advantage, causing the host to behave in an abnormal manner.

Cosmic 'hand' hitting a wall

Cosmic dawn occurred 250 to 350 million years after Big Bang

Pleistocene sediment DNA reveals hominin and faunal turnovers at Denisova Cave

Abstract

Denisova Cave in southern Siberia is the type locality of the Denisovans, an archaic hominin group who were related to Neanderthals. The dozen hominin remains recovered from the deposits also include Neanderthals and the child of a Neanderthal and a Denisovan, which suggests that Denisova Cave was a contact zone between these archaic hominins. However, uncertainties persist about the order in which these groups appeared at the site, the timing and environmental context of hominin occupation, and the association of particular hominin groups with archaeological assemblages. Here we report the analysis of DNA from 728 sediment samples that were collected in a grid-like manner from layers dating to the Pleistocene epoch. We retrieved ancient faunal and hominin mitochondrial (mt)DNA from 685 and 175 samples, respectively. The earliest evidence for hominin mtDNA is of Denisovans, and is associated with early Middle Palaeolithic stone tools that were deposited approximately 250,000 to 170,000 years ago; Neanderthal mtDNA first appears towards the end of this period. We detect a turnover in the mtDNA of Denisovans that coincides with changes in the composition of faunal mtDNA, and evidence that Denisovans and Neanderthals occupied the site repeatedly—possibly until, or after, the onset of the Initial Upper Palaeolithic at least 45,000 years ago, when modern human mtDNA is first recorded in the sediments.

Main

Denisova Cave consists of three chambers (designated Main, East and South Chambers) that contain deposits with stratigraphic sequences extending from the Middle Pleistocene to the Holocene epoch. The Pleistocene deposits have chronologies that have been constructed from the radiocarbon dating of bone, tooth and charcoal5 (to around 50 thousand years ago (ka)) and optical dating of sediments8 (to more than 300 ka). Optical ages for Main and East Chambers (Fig. 1a–c) can be aligned on a common time scale (Extended Data Fig. 1) but excavations are ongoing in South Chamber, where layers are only tentatively recognized. Mitochondrial DNA and nuclear DNA have been recovered from eight hominin fossils, enabling four to be assigned to Denisovans (Denisova 2, Denisova 3, Denisova 4 and Denisova 8), three to Neanderthals (Denisova 5, Denisova 9 and Denisova 15), and one to the child of a Neanderthal and a Denisovan (Denisova 11). However, there are too few fossils to enable the detailed reconstruction of the timing and sequence of hominin occupation, and the association of the early Middle Palaeolithic, middle Middle Palaeolithic and Initial Upper Palaeolithic assemblages identified at the site with specific hominin groups. Moreover, two Denisovan fossils (Denisova 3 and Denisova 4)—but no modern human remains—have been recovered from the Initial Upper Palaeolithic layers, so it is debated whether archaic hominins or modern humans created the associated ornaments and bone tools.

обзор на phys.org

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