(18:00)📌 ال structure سلايد 3 ، إسمه T-plug shape.⚗️
(44:50)📌 ❓Why is Atropine generalized muscarinic blocker?
Atropine is a tertiary amine alkaloid with a bulky tropane ring and an ester linkage. These structural features allow atropine to fit into the binding pockets of all muscarinic acetylcholine receptors (M1–M5), that acts as a competitive antagonist at all muscarinic acetylcholine receptors (M1–M5). Its structure allows it to non-selectively block these receptors by competing with acetylcholine at the binding site, preventing parasympathetic responses. This lack of specificity for any receptor subtype makes it a generalized muscarinic blocker.